![]() ![]() Overall, our results indicate that the wound-healing activities of AAP can be applied in an AAP-based product for wound management.Īuricularia auricula-judae collagen synthesis fibroblasts proliferation in vivo skin wound healing keratinocytes proliferation medicinal mushroom polysaccharide-rich extract wound healing. 2010 (Chang and Miles 2004 Morales et al. These beneficial plant compounds help combat oxidative stress in your body, which has been linked to inflammation and a range of diseases (9Trusted Source, 10Trusted Source). Auricularia is the fourth most cultivated mushroom genus after Agaricus, Lentinula and Pleurotus in the world (Chang and Miles 2004 Tang et al. Used for bleeding hemorrhoids, dropsy and sore throat. Mushrooms, including Auricularia species, are generally high in antioxidants. However, compared with polysaccharides of Auricularia auricula and Auricularia cornea, which are widely cultivated in China, there are few studies on the edible value and processing properties of novel polysaccharide of deer tripe mushroom. Folkloric - Used for metrorrhagia, urinary tract diseases, dysentery. Polysaccharide is the main active component in Auricularia. Commonly known as wood ear, Auricularia auricula is the first recorded cultivated mushroom (Chang 1993). A popular ingredient for chop-suey, hot and sour soup, sotanghon, pinsic, etc. Specifically, the AAP significantly accelerated the wound closure in a mice skin wound-healing model on day 9 (2.5%AAP, p = 0.031 vs. - Imported in dry state from China and Japan. AAP significantly promoted both fibroblast and keratinocyte proliferation, migration, and invasion, along with augmentation of the wound-healing process by increasing collagen synthesis and decreasing E-cadherin expression (All p < 0.05). AAP displayed antioxidant activity in vitro and was able to abort UVB-induced intracellular ROS production in human fibroblasts in cellulo. ![]() The main sugar composition of AAP includes mannose, galactose, and glucose. AAP contained high amounts of polysaccharides (349.83 ± 5.00 mg/g extract) with a molecular weight of 158 kDa. In this study, we have reported on the mechanisms that promote the wound-healing effects of a water-soluble polysaccharide-rich extract obtained from A. Auricularia auricula-judae, a nutrient-rich mushroom used in traditional medicine, is a macrofungi that exhibits various biological properties.
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